This catalogue serves as a living inventory of the Depression Grand Challenge’s research studies, treatment implementations, programming, and other activities. Each list item links to an accompanying fact sheet with an overview and details about the activity. Use the sections below to quickly navigate:
General Information
Research Centers
Unique Assets
Research Studies
⇒ An arrow indicates projects that are housed outside the Depression Grand Challenge because they did not require or, at the time of submission for funding, predated an existing DGC capability or resource.
Digital Sensing Studies
- Research objective: Discover causes & trajectories
- Digital Mental Health Study
- National Digital Mental Health Study
- HARMONY - co-listed as treatment studyOPTIMA & ILIAD
Genetics Studies
Research objective: Discover causes & trajectories
- ⇒ BD2 Genomics Platform
- ⇒ Populations Underrepresented in Mental Illness Association Studies (PUMAS)
- ⇒ Impact of the COVID-19 Pandemic on Severe Mental Illness
- ⇒ Latin American Biobank for Large-Scale Genetics Research on Severe Mental Illness (LAB-SMI)
- ⇒ Identifying Genetic Causes of Depression in a Deeply Phenotyped Population from South Korea
- ⇒ Improving Interpretability of Genetic Studies of Major Depressive Disorder to Identify Risk Genes⇒ Combining Voice & Genetic Information to Detect Heterogeneity in Major Depressive Disorder
Mechanisms Studies
- Research objective: Elucidate mechanisms
- ⇒ Uncovering Microbial Modifiers of Antidepressant Responses During Pregnancy
- ⇒ Developing a Pathway from Genetic Locus to Gene for Complex Traits in Rodents
Treatment Studies
- Research objective: Develop new & better treatments
- STAND at ELAC - part of ALACRITY Center
- HARMONY - co-listed as digital sensing study
- New Moms Mood Tracking & Wellbeing
- Calming Minds (STAND at IVC)
- ⇒ Maternal-Child Interaction Study
STAND Overview
Site-Specific STANDs
- Formal research and service implementations of STAND at institutions
- STAND at ELAC - co-listed as treatment study STAR (STAND at UCLA)
- Calming Minds (STAND at IVC) - co-listed as treatment study
- STAND at ELAC Demonstration Project - sunsetted
STAND Resources
Free, public resources leveraging components of the STAND system of care