A preprint protocol article describing the design and implementation of the landmark Digital Mental Health Study was posted on medRxiv on Oct. 1, 2025 and has been submitted for publication in a peer-reviewed journal. Senior authors of this protocol article from UCLA include Nelson Freimer, MD, UCLA Depression Grand Challenge director and DMHS principal investigator; Michelle Craske, PhD, DGC co-director.
Causes & Trajectories
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The UCLA Depression Grand Challenge is contributing its expertise to a new effort seeking to identify common measures and establish standards for the use of digital sensing data in mental health research and treatment.
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The Digital Health Measurement Collaborative Community (DATAcc) by the Digital Medicine Society (DiMe), in which Depression Grand Challenge team members participated, released a report on Feb. 4, 2025, detailing evidence-based, actionable recommendations to drive interest, investment, and direction for sensor-based digital health technology research and innovation.
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The Perspective, “Advancing digital sensing in mental health research,” draws on insights, findings and related reports generated from the 2023 Workshop on Advancing Digital Sensing Tools for Mental Health, hosted by UCLA and sponsored by Wellcome, the National Institute of Mental Health and the DGC.
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Preliminary findings from the UCLA Depression Grand Challenge’s Digital Mental Health Study were featured in a May 2, 2024, Time publication focused on the 2024 TIME100 Most Influential People in Health.
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The UCLA Depression Grand Challenge achieved a significant milestone on April 30, 2024, when the Digital Mental Health Study (DMHS) completed data collection, 26 months after starting.
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The UCLA Depression Grand Challenge is part of a consortium tapped by Wellcome, a global charitable organization that funds discovery research, to conduct a scoping research project on digital sensing for mental health research.
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The UCLA Depression Grand Challenge collaborated with a consortium led by The Digital Health Measurement Collaborative Community (DATAcc) by the Digital Medicine Society (DiMe) to submit a proposal to Wellcome, a global charitable organization that funds discovery research, for the opportunity to conduct scoping research to assess how digital sensing technologies may be leveraged to detect and treat mental health conditions.
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Wellcome, a global charitable organization that funds discovery research, issued a request for proposals to extend the work of the digital sensing workshop, hosted at UCLA and co-sponsored by Wellcome and the National Institute of Mental Health in March 2023.
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UCLA and global experts seek colleague input for digital sensing in mental health research standards
Leading mental health and computer science researchers, industry experts, advocates and funders who participated in the Digital Sensing Workshop held at UCLA in the winter of 2023 are seeking additional review and input from colleagues and other stakeholders for a shared vision, common standards and recommendations they created to facilitate the use of digital sensing technologies in mental health research.
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